What is CBD and how does it interact with the body?

CBD stands for Cannabidiol. It is one of over 100 different cannabinoids found in cannabis plants. CBD is a non-competitive antagonist. Just wait - I’ll explain! A non-competitive antagonist binds to the non-antagonist site of a receptor to prevent its activation. This blocks or dampens a biological response rather than activate it. Bear with me, the point is coming. In the human body the biological response to an injury is typically pain, so by blocking or dampening this response CBD has shown to decrease the feeling of pain and the decrease the inflammatory response. This action is similar to other analgesics as they are creating an inability to feel pain. 

Another example of a non-competitive antagonist and analgesic is ketamine. Both ketamine and CBD have similar benefits and promising studies have been released showing success in the treatment of chronic pain, depression, anxiety and post traumatic stress disorder. 

Many associate CBD with marijuana. CBD is derived from the hemp plant which is related to the marijuana plant, but CBD has no psychoactive properties because of the limit of THC present (the mind-altering substance found in marijuana). In many ways CBD has antipsychotic effects which is why many pair it with THC to help calm anxiety and psychoactive effects for a more desirable outcome.

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References:

 https://derangedphysiology.com/main/cicm-primary-exam/required-reading/pharmacodynamics/Chapter%20418/competitive-and-non-competitive-antagonists 

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557112/#:~:text=They%20concluded%20that%20CB1%20receptors,anti%2Dinflammation%20%5B20%5D. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700528/ 

https://en.wikipedia.org/wiki/Receptor_antagonist 

https://journals.lww.com/pain/fulltext/2019/01000/cannabidiol_modulates_serotonergic_transmission.16.aspx